[9] Harlequins 5-35 London Irish [12] 2018-04-07 14:00
Stadium: London Round: 19
Referee: Ian Tempest Home Manager: Mark Mapletoft Away Manager: Nick Kennedy
Head to Head
| Premiership Rugby | 2017/09/02 15:45 | London Irish v Harlequins | L | 39-29 |
| Premiership Rugby | 2016/05/01 14:00 | London Irish v Harlequins | W | 25-32 |
| European Rugby Challenge Cup | 2016/04/09 19:05 | Harlequins v London Irish | W | 38-30 |
| Premiership Rugby | 2015/12/05 15:00 | Harlequins v London Irish | W | 38-7 |
| Premiership Rugby | 2015/03/07 15:00 | Harlequins v London Irish | W | 26-20 |
| Premiership Rugby | 2014/09/06 15:30 | London Irish v Harlequins | W | 15-20 |