[28] Ohio State 52-12 Michigan State [84] 2020-12-05 17:00
Stadium: Spartan Stadium Round: 1
Head to Head
| NCAAF | 2019/10/05 23:30 | Michigan State v Ohio State | W | 10-34 |
| NCAAF | 2018/11/10 17:00 | Ohio State v Michigan State | W | 26-6 |
| NCAAF | 2017/11/11 17:00 | Michigan State v Ohio State | W | 3-48 |
| NCAAF | 2016/11/19 17:00 | Ohio State v Michigan State | W | 17-16 |
| NCAAF | 2015/11/21 20:30 | Ohio State v Michigan State | L | 14-17 |
| NCAAF | 2014/11/09 01:00 | Michigan State v Ohio State | W | 37-49 |
| NCAAF | 2012/09/29 12:00 | Michigan State v Ohio State | W | 16-17 |
| NCAAF | 2011/10/01 12:00 | Ohio State v Michigan State | L | 7-10 |
| NCAAF | 2008/10/18 12:00 | Michigan State v Ohio State | W | 7-45 |
| NCAAF | 2007/10/20 12:00 | Ohio State v Michigan State | W | 24-17 |
| NCAAF | 2006/10/14 12:00 | Michigan State v Ohio State | W | 7-38 |
| NCAAF | 2005/10/15 12:00 | Ohio State v Michigan State | W | 35-24 |
| NCAAF | 2004/11/06 12:00 | Michigan State v Ohio State | W | 19-32 |
| NCAAF | 2003/11/08 12:00 | Ohio State v Michigan State | W | 33-23 |
| NCAAF | 2000/11/04 12:00 | Ohio State v Michigan State | W | 27-13 |