Stadium: Roy Kidd Stadium Round: 1
Home Manager: Mark Elder Away Manager: Kim Dameron
| NCAAF | 2018/10/20 19:00 | Eastern Kentucky v Murray State | L | 6-34 |
| NCAAF | 2018/10/13 19:00 | Eastern Kentucky v Tennessee Martin | W | 35-34 |
| NCAAF | 2018/10/06 20:00 | Jacksonville State v Eastern Kentucky | L | 56-7 |
| NCAAF | 2018/09/22 20:00 | SE Missouri St v Eastern Kentucky | W | 14-23 |
| NCAAF | 2018/09/15 20:00 | Eastern Kentucky v Bowling Green | L | 35-42 |
| NCAAF | 2018/09/08 22:30 | Eastern Kentucky v Marshall | L | 16-32 |
| NCAAF | 2018/08/30 23:00 | Morehead State v Eastern Kentucky | W | 23-49 |
| NCAAF | 2017/11/18 18:00 | Eastern Kentucky v St.Francis (PA) | W | 14-10 |
| NCAAF | 2018/10/20 19:00 | Eastern Illinois v Tennessee Martin | W | 24-21 |
| NCAAF | 2018/10/13 20:00 | Eastern Illinois v Jacksonville State | L | 22-49 |
| NCAAF | 2018/10/06 23:00 | Murray State v Eastern Illinois | L | 48-41 |
| NCAAF | 2018/09/29 23:00 | Eastern Illinois v Tennessee Tech | W | 52-38 |
| NCAAF | 2018/09/22 19:00 | Tennessee State v Eastern Illinois | L | 41-40 |
| NCAAF | 2018/09/15 23:00 | Indiana State v Eastern Illinois | L | 55-41 |
| NCAAF | 2018/09/08 23:30 | Eastern Illinois v Illinois State | L | 10-48 |
| NCAAF | 2018/09/01 20:00 | Eastern Illinois v Arkansas | L | 20-55 |