[3] Defensor Sporting 2-1 Danubio [7] 2022-07-17 21:30
Stadium: Estadio Luis Franzini Round: 5
Referee: Mathias De Armas Home Manager: Marcelo Fabian Mendez Russo Away Manager: Jorge Daniel Fossati Lurachi
Head to Head
| Uruguay - Apertura | 2022/05/22 18:30 | Danubio v Defensor Sporting | W | 1-2 |
| Amerika - Vennskapskamper | 2022/01/17 00:30 | Defensor Sporting v Danubio | L | 0-2 |
| Uruguay - Segunda | 2021/11/24 01:15 | Defensor Sporting v Danubio | L | 0-1 |
| Uruguay - Segunda | 2021/08/14 19:00 | Danubio v Defensor Sporting | W | 0-1 |
| Uruguay - Clausura | 2021/02/28 22:15 | Defensor Sporting v Danubio | D | 1-1 |
| Uruguay - Torneo Intermedio | 2020/10/18 18:00 | Danubio v Defensor Sporting | D | 0-0 |
| Uruguay - Apertura | 2020/09/06 18:00 | Danubio v Defensor Sporting | D | 0-0 |
| Uruguay - Clausura | 2019/11/02 19:00 | Defensor Sporting v Danubio | L | 1-2 |
Home History
| Uruguay - Torneo Intermedio | 2022/07/10 19:00 | Boston River v Defensor Sporting | W | 2-3 |
| Uruguay - Torneo Intermedio | 2022/06/25 20:30 | Defensor Sporting v Cerro Largo | W | 1-0 |
| Uruguay - Torneo Intermedio | 2022/06/19 23:00 | Cerrito v Defensor Sporting | W | 1-2 |
| Uruguay - Torneo Intermedio | 2022/06/13 22:30 | Defensor Sporting v Nacional De Football | L | 0-1 |
| Uruguay - Apertura | 2022/06/05 15:00 | Rentistas v Defensor Sporting | L | 1-0 |
| Uruguay - Apertura | 2022/05/29 20:30 | Defensor Sporting v Deportivo Maldonado | D | 1-1 |
| Uruguay - Apertura | 2022/05/22 18:30 | Danubio v Defensor Sporting | W | 1-2 |
| Uruguay - Apertura | 2022/05/14 21:00 | Defensor Sporting v Nacional De Football | L | 0-2 |
Away History
| Uruguay - Torneo Intermedio | 2022/07/10 15:00 | Danubio v CA River Plate | L | 1-3 |
| Uruguay - Torneo Intermedio | 2022/06/25 18:00 | Danubio v Nacional De Football | L | 0-1 |
| Uruguay - Torneo Intermedio | 2022/06/20 19:00 | Boston River v Danubio | L | 2-0 |
| Uruguay - Torneo Intermedio | 2022/06/12 18:00 | Danubio v Cerro Largo | D | 1-1 |
| Uruguay - Apertura | 2022/06/05 18:00 | Danubio v Nacional De Football | W | 2-1 |
| Uruguay - Apertura | 2022/05/27 18:00 | Albion FC v Danubio | W | 1-2 |
| Uruguay - Apertura | 2022/05/22 18:30 | Danubio v Defensor Sporting | L | 1-2 |
| Uruguay - Apertura | 2022/05/15 16:15 | Atletico Fenix Montevideo v Danubio | D | 0-0 |