[2] Boston River 2-3 Defensor Sporting [4] 2022-07-10 19:00
Stadium: Estadio Parque Artigas Round: 4
Referee: Leodan Frankin Gonzalez Cabrera Home Manager: Ignacio Ithurralde Away Manager: Marcelo Mendez
Head to Head
| Uruguay - Apertura | 2022/03/21 22:00 | Boston River v Defensor Sporting | D | 1-1 |
| Uruguay - Clausura | 2021/03/12 21:45 | Defensor Sporting v Boston River | W | 1-2 |
| Uruguay - Torneo Intermedio | 2021/01/13 21:00 | Defensor Sporting v Boston River | D | 1-1 |
| Uruguay - Apertura | 2020/09/13 15:45 | Boston River v Defensor Sporting | D | 1-1 |
| Uruguay - Clausura | 2019/10/25 19:00 | Boston River v Defensor Sporting | L | 1-4 |
| Uruguay - Torneo Intermedio | 2019/08/31 18:00 | Defensor Sporting v Boston River | D | 2-2 |
| Uruguay - Apertura | 2019/04/07 19:00 | Defensor Sporting v Boston River | D | 0-0 |
| Uruguay - Clausura | 2018/10/28 19:30 | Boston River v Defensor Sporting | W | 3-1 |
Home History
| Uruguay - Torneo Intermedio | 2022/06/26 13:00 | CA River Plate v Boston River | W | 0-1 |
| Uruguay - Torneo Intermedio | 2022/06/20 19:00 | Boston River v Danubio | W | 2-0 |
| Uruguay - Torneo Intermedio | 2022/06/14 18:00 | Plaza Colonia v Boston River | D | 0-0 |
| Uruguay - Apertura | 2022/06/06 21:30 | Montevideo Wanderers v Boston River | W | 1-2 |
| Uruguay - Apertura | 2022/05/28 20:30 | Boston River v Torque | W | 3-1 |
| Uruguay - Apertura | 2022/05/21 22:30 | Penarol v Boston River | L | 1-0 |
| Uruguay - Apertura | 2022/05/16 21:00 | Boston River v Liverpool Montevideo | L | 2-3 |
| Uruguay - Apertura | 2022/05/08 16:00 | Rentistas v Boston River | W | 0-1 |
Away History
| Uruguay - Torneo Intermedio | 2022/06/25 20:30 | Defensor Sporting v Cerro Largo | W | 1-0 |
| Uruguay - Torneo Intermedio | 2022/06/19 23:00 | Cerrito v Defensor Sporting | W | 1-2 |
| Uruguay - Torneo Intermedio | 2022/06/13 22:30 | Defensor Sporting v Nacional De Football | L | 0-1 |
| Uruguay - Apertura | 2022/06/05 15:00 | Rentistas v Defensor Sporting | L | 1-0 |
| Uruguay - Apertura | 2022/05/29 20:30 | Defensor Sporting v Deportivo Maldonado | D | 1-1 |
| Uruguay - Apertura | 2022/05/22 18:30 | Danubio v Defensor Sporting | W | 1-2 |
| Uruguay - Apertura | 2022/05/14 21:00 | Defensor Sporting v Nacional De Football | L | 0-2 |
| Uruguay - Apertura | 2022/05/07 16:00 | Albion FC v Defensor Sporting | W | 0-3 |