Stadium: Reitz Arena
Home Manager: Tavaras Hardy Away Manager: Gerald Gillion
| NCAAB | 2021/11/28 19:00 | Chicago St v Bowling Green | L | 57-75 |
| NCAAB | 2021/11/23 03:00 | Chicago St v Pacific | L | 58-74 |
| NCAAB | 2021/11/20 21:00 | Chicago St v UC Santa Barbara | L | 50-81 |
| NCAAB | 2021/11/17 01:00 | Chicago St v Loyola Chicago | L | 56-92 |
| NCAAB | 2021/11/13 01:00 | SIU Edwardsville v Chicago St | W | 56-67 |
| NCAAB | 2021/11/10 01:00 | St. Thomas (MN) v Chicago St | W | 72-77 |
| NCAAB | 2020/12/20 20:00 | Chicago St v Drake | L | 67-111 |
| NCAAB | 2020/12/19 00:00 | Chicago St v Northern Illinois | L | 54-64 |
| NCAAB | 2021/11/28 19:00 | Loyola Maryland v Fairfield | W | 75-70 |
| NCAAB | 2021/11/24 20:00 | Elizabethtown v Loyola Maryland | W | 42-69 |
| NCAAB | 2021/11/18 00:00 | Loyola Maryland v Coppin State | L | 49-71 |
| NCAAB | 2021/11/14 15:30 | Lipscomb v Loyola Maryland | L | 70-65 |
| NCAAB | 2021/11/13 22:00 | Loyola Maryland v Coll Of Charleston | L | 72-79 |
| NCAAB | 2021/11/12 21:00 | Loyola Maryland v South Carolina State | W | 75-65 |
| NCAAB | 2021/11/10 00:00 | Loyola Maryland v North Carolina | L | 67-83 |
| NCAAB | 2021/03/14 16:00 | Loyola Maryland v Colgate | L | 72-85 |