Stadium: Macon Centreplex
| SPHL | 2021/12/04 01:05 | Pensacola Ice Flyers v Macon Mayhem | L | 7-1 |
| SPHL | 2021/11/25 01:05 | Macon Mayhem v Pensacola Ice Flyers | L | 4-6 |
| SPHL | 2021/05/15 22:30 | Macon Mayhem v Pensacola Ice Flyers | L | 1-4 |
| SPHL | 2021/05/15 00:05 | Pensacola Ice Flyers v Macon Mayhem | L | 4-2 |
| SPHL | 2021/04/16 23:30 | Macon Mayhem v Pensacola Ice Flyers | W | 5-3 |
| SPHL | 2021/04/09 22:05 | Macon Mayhem v Pensacola Ice Flyers | W | 9-3 |
| SPHL | 2021/04/08 23:35 | Macon Mayhem v Pensacola Ice Flyers | W | 5-0 |
| SPHL | 2021/03/28 00:05 | Pensacola Ice Flyers v Macon Mayhem | W | 2-4 |
| SPHL | 2021/12/04 01:05 | Pensacola Ice Flyers v Macon Mayhem | L | 7-1 |
| SPHL | 2021/12/03 01:00 | Birmingham Bulls v Macon Mayhem | W | 0-3 |
| SPHL | 2021/11/27 23:30 | Macon Mayhem v Evansville Thunderbolts | W | 3-2 |
| SPHL | 2021/11/27 00:30 | Macon Mayhem v Evansville Thunderbolts | L | 0-3 |
| SPHL | 2021/11/25 01:05 | Macon Mayhem v Pensacola Ice Flyers | L | 4-6 |
| SPHL | 2021/11/20 23:00 | Fayetteville Marksmen v Macon Mayhem | L | 6-2 |
| SPHL | 2021/11/20 00:00 | Fayetteville Marksmen v Macon Mayhem | L | 5-2 |
| SPHL | 2021/11/14 21:00 | Macon Mayhem v Fayetteville Marksmen | L | 1-3 |
| SPHL | 2021/12/04 01:05 | Pensacola Ice Flyers v Macon Mayhem | W | 7-1 |
| SPHL | 2021/11/27 01:00 | Huntsville Havoc v Pensacola Ice Flyers | L | 5-2 |
| SPHL | 2021/11/25 01:05 | Macon Mayhem v Pensacola Ice Flyers | W | 4-6 |
| SPHL | 2021/11/21 01:05 | Pensacola Ice Flyers v Quad City Storm | W | 3-2 |
| SPHL | 2021/11/20 01:05 | Pensacola Ice Flyers v Quad City Storm | L | 3-4 |
| SPHL | 2021/11/14 01:05 | Pensacola Ice Flyers v Huntsville Havoc | L | 2-4 |
| SPHL | 2021/11/13 01:00 | Huntsville Havoc v Pensacola Ice Flyers | L | 5-2 |
| SPHL | 2021/11/07 00:05 | Pensacola Ice Flyers v Birmingham Bulls | W | 4-2 |