Stadium: Roy Kidd Stadium Round: 1
Home Manager: Walt Wells Away Manager: Todd Whitten
| NCAAF | 2021/09/25 23:00 | Tarleton State v N. Mexico H. Cowboys | W | 40-21 |
| NCAAF | 2021/09/18 23:00 | Southern Utah v Tarleton State | L | 40-35 |
| NCAAF | 2021/09/11 23:00 | Tarleton State v Fort Lewis Skyhawks | W | 54-7 |
| NCAAF | 2021/09/04 23:00 | Tarleton State v Stephen F. Austin | L | 10-20 |
| NCAAF | 2021/04/01 23:00 | Tarleton State v East Central Tigers | L | 14-21 |
| NCAAF | 2021/03/27 23:00 | Tarleton State v Northeastern State Riverhawks | W | 38-0 |
| NCAAF | 2021/03/20 23:00 | Tarleton State v Midwestern State University Mustangs | W | 33-21 |
| NCAAF | 2021/03/14 02:00 | Tarleton State v Utah Tech | W | 37-15 |
| NCAAF | 2021/09/25 19:00 | Austin Peay v Eastern Kentucky | W | 27-35 |
| NCAAF | 2021/09/18 23:00 | Indiana State v Eastern Kentucky | L | 23-21 |
| NCAAF | 2021/09/11 23:00 | Eastern Kentucky v Louisville | L | 3-30 |
| NCAAF | 2021/09/04 22:00 | Eastern Kentucky v Western Carolina | W | 31-28 |
| NCAAF | 2020/11/21 20:00 | Western Carolina v Eastern Kentucky | W | 17-49 |
| NCAAF | 2020/11/14 21:00 | Eastern Kentucky v Central Arkansas | L | 25-37 |
| NCAAF | 2020/11/07 20:00 | Stephen F. Austin v Eastern Kentucky | L | 24-6 |
| NCAAF | 2020/10/24 19:00 | Eastern Kentucky v Central Arkansas | W | 31-28 |