Stadium: Kessler Stadium Round: 1
Home Manager: Kevin Callahan Away Manager: Bob Chesney
| NCAAF | 2019/11/30 17:00 | Holy Cross v Monmouth | L | 27-44 |
| NCAAF | 2017/10/07 17:05 | Holy Cross v Monmouth | L | 36-48 |
| NCAAF | 2021/09/18 16:00 | Holy Cross v Yale | W | 20-17 |
| NCAAF | 2021/09/11 18:00 | Merrimack v Holy Cross | L | 35-21 |
| NCAAF | 2021/09/04 16:00 | Holy Cross v Connecticut | W | 38-28 |
| NCAAF | 2021/04/24 19:00 | Holy Cross v South Dakota State | L | 3-31 |
| NCAAF | 2021/04/17 18:00 | Holy Cross v Bucknell | W | 33-10 |
| NCAAF | 2021/03/27 17:00 | Fordham v Holy Cross | W | 24-34 |
| NCAAF | 2021/03/13 17:00 | Holy Cross v Lehigh | W | 20-3 |
| NCAAF | 2019/11/30 17:00 | Holy Cross v Monmouth | L | 27-44 |
| NCAAF | 2021/09/18 22:00 | Monmouth v Charleston Southern | W | 41-14 |
| NCAAF | 2021/09/11 22:00 | Monmouth v Fordham | W | 26-23 |
| NCAAF | 2021/09/04 23:00 | Monmouth v Middle Tennessee St. | L | 15-50 |
| NCAAF | 2021/04/24 16:00 | Monmouth v Sam Houston State | L | 15-21 |
| NCAAF | 2021/04/10 17:00 | Kennesaw State v Monmouth | W | 17-42 |
| NCAAF | 2021/04/03 16:00 | Monmouth v Gardner Webb | W | 48-19 |
| NCAAF | 2021/03/27 17:00 | Charleston Southern v Monmouth | W | 17-35 |
| NCAAF | 2019/12/07 18:00 | Monmouth v James Madison | L | 21-66 |