[60] Western Michigan 42-21 Northern Illinois [31] 2021-11-24 00:00
Stadium: Brigham Field at Huskie Stadium Round: 1
Home Manager: Thomas Hammock Away Manager: Tim Lester
Head to Head
| NCAAF | 2020/11/28 17:00 | Northern Illinois v Western Michigan | W | 27-30 |
| NCAAF | 2019/11/27 00:00 | Western Michigan v Northern Illinois | L | 14-17 |
| NCAAF | 2018/11/21 00:00 | Northern Illinois v Western Michigan | W | 21-28 |
| NCAAF | 2017/11/16 00:00 | Western Michigan v Northern Illinois | L | 31-35 |
| NCAAF | 2016/10/08 22:30 | Northern Illinois v Western Michigan | W | 30-45 |
| NCAAF | 2015/11/19 01:00 | Northern Illinois v Western Michigan | L | 27-19 |
| NCAAF | 2014/11/28 16:00 | Western Michigan v Northern Illinois | L | 21-31 |
| NCAAF | 2012/10/27 12:00 | Western Michigan v Northern Illinois | L | 34-48 |
Home History
| NCAAF | 2021/11/17 00:30 | Western Michigan v Eastern Michigan | L | 21-22 |
| NCAAF | 2021/11/10 00:00 | Akron v Western Michigan | W | 40-45 |
| NCAAF | 2021/11/03 23:00 | Central Michigan v Western Michigan | L | 42-30 |
| NCAAF | 2021/10/23 19:30 | Western Michigan v Toledo | L | 15-34 |
| NCAAF | 2021/10/16 19:30 | Kent State v Western Michigan | W | 31-64 |
| NCAAF | 2021/10/09 19:30 | Ball State v Western Michigan | L | 45-20 |
| NCAAF | 2021/10/02 16:00 | Western Michigan v Buffalo | W | 24-17 |
| NCAAF | 2021/09/25 18:00 | San Jose State v Western Michigan | W | 3-23 |
Away History
| NCAAF | 2021/11/18 00:00 | Northern Illinois v Buffalo | W | 33-27 |
| NCAAF | 2021/11/11 00:00 | Ball State v Northern Illinois | W | 29-30 |
| NCAAF | 2021/11/03 23:00 | Northern Illinois v Kent State | L | 47-52 |
| NCAAF | 2021/10/23 16:00 | Northern Illinois v Central Michigan | W | 39-38 |
| NCAAF | 2021/10/16 19:30 | Bowling Green v Northern Illinois | W | 26-34 |
| NCAAF | 2021/10/09 16:00 | Northern Illinois v Toledo | W | 22-20 |
| NCAAF | 2021/10/02 18:30 | Eastern Michigan v Northern Illinois | W | 20-27 |
| NCAAF | 2021/09/25 18:30 | Maine v Northern Illinois | W | 14-41 |