Home History
| Europa - Vennskapskamper | 2021/07/06 16:00 | Dundee v Leyton Orient | L | 3-0 |
| England - League 2 | 2021/05/08 15:00 | Salford City v Leyton Orient | L | 3-0 |
| England - League 2 | 2021/05/01 14:00 | Leyton Orient v Carlisle | L | 2-3 |
| England - League 2 | 2021/04/24 14:00 | Southend v Leyton Orient | L | 2-1 |
| England - League 2 | 2021/04/20 18:00 | Leyton Orient v Cambridge Utd | L | 2-4 |
| England - League 2 | 2021/04/17 11:30 | Leyton Orient v Barrow | W | 2-0 |
| England - League 2 | 2021/04/13 18:00 | Harrogate Town v Leyton Orient | D | 2-2 |
| England - League 2 | 2021/04/10 14:00 | Cheltenham v Leyton Orient | L | 1-0 |
Away History
| Europa - Vennskapskamper | 2021/07/09 12:00 | Dundee v West Ham | D | 2-2 |
| England - Premier League | 2021/05/23 15:00 | West Ham v Southampton | W | 3-0 |
| England - Premier League | 2021/05/19 19:15 | West Brom v West Ham | W | 1-3 |
| England - Premier League | 2021/05/15 19:00 | Brighton v West Ham | D | 1-1 |
| England - Premier League | 2021/05/09 15:30 | West Ham v Everton | L | 0-1 |
| England - Premier League | 2021/05/03 19:15 | Burnley v West Ham | W | 1-2 |
| England - Premier League | 2021/04/24 16:30 | West Ham v Chelsea | L | 0-1 |
| England - Premier League | 2021/04/17 11:30 | Newcastle v West Ham | L | 3-2 |