[12] Tranmere 0-1 Sutton Utd [9] 2021-11-13 15:00
Stadium: Prenton Park Round: 16
Referee: Will Finnie Home Manager: Micky Mellon Away Manager: Matt Gray
Head to Head
| England - National League | 2017/12/23 15:00 | Sutton Utd v Tranmere | W | 1-3 |
| England - National League | 2017/08/12 14:00 | Tranmere v Sutton Utd | L | 0-1 |
| England - National League | 2017/04/04 18:45 | Tranmere v Sutton Utd | W | 3-2 |
| England - National League | 2016/09/17 11:15 | Sutton Utd v Tranmere | L | 1-0 |
Home History
| England - EFL Trophy | 2021/11/09 19:00 | Tranmere v Oldham | W | 3-2 |
| England - FA Cup | 2021/11/06 15:00 | Crawley Town v Tranmere | W | 0-1 |
| England - League 2 | 2021/10/30 14:00 | Mansfield v Tranmere | L | 2-0 |
| England - League 2 | 2021/10/23 14:00 | Tranmere v Northampton | L | 0-2 |
| England - League 2 | 2021/10/19 18:45 | Harrogate Town v Tranmere | D | 2-2 |
| England - League 2 | 2021/10/16 14:00 | Carlisle v Tranmere | W | 0-1 |
| England - League 2 | 2021/10/08 18:45 | Tranmere v Colchester | W | 2-0 |
| England - EFL Trophy | 2021/10/05 18:00 | Salford City v Tranmere | W | 0-2 |
Away History
| England - EFL Trophy | 2021/11/09 19:45 | Sutton Utd v AFC Wimbledon | W | 1-0 |
| England - FA Cup | 2021/11/06 15:00 | Hayes & Yeading v Sutton Utd | W | 0-1 |
| England - League 2 | 2021/10/30 14:00 | Sutton Utd v Walsall | L | 0-1 |
| England - League 2 | 2021/10/26 18:45 | Colchester v Sutton Utd | W | 1-3 |
| England - League 2 | 2021/10/23 14:00 | Rochdale v Sutton Utd | L | 3-2 |
| England - League 2 | 2021/10/19 18:45 | Sutton Utd v Swindon | L | 1-2 |
| England - League 2 | 2021/10/16 14:00 | Crawley Town v Sutton Utd | W | 0-1 |
| England - EFL Trophy | 2021/10/12 18:45 | Portsmouth v Sutton Utd | W | 0-2 |