[3] Benfica 2-1 Santa Clara [7] 2021-04-26 18:00
Stadium: Estadio do Sport Lisboa e Benfica Round: 29
Referee: Helder Miguel Azevedo Malheiro Home Manager: Jorge Jesus Away Manager: Daniel Ramos
Head to Head
| Portugal - Primeira Liga | 2021/01/04 17:00 | Santa Clara v Benfica | D | 1-1 |
| Portugal - Primeira Liga | 2020/06/23 18:15 | Benfica v Santa Clara | L | 3-4 |
| Portugal - Primeira Liga | 2019/11/09 18:00 | Santa Clara v Benfica | W | 1-2 |
| Portugal - Primeira Liga | 2019/05/18 17:30 | Benfica v Santa Clara | W | 4-1 |
| Portugal - Primeira Liga | 2019/01/11 19:00 | Santa Clara v Benfica | W | 0-2 |
Home History
| Portugal - Primeira Liga | 2021/04/22 18:00 | Portimonense v Benfica | W | 1-5 |
| Portugal - Primeira Liga | 2021/04/17 17:00 | Benfica v Gil Vicente | L | 1-2 |
| Portugal - Primeira Liga | 2021/04/10 19:30 | Pacos Ferreira v Benfica | W | 0-5 |
| Portugal - Primeira Liga | 2021/04/05 18:00 | Benfica v Maritimo | W | 1-0 |
| Portugal - Primeira Liga | 2021/03/21 20:00 | Braga v Benfica | W | 0-2 |
| Portugal - Primeira Liga | 2021/03/13 18:00 | Benfica v Boavista | W | 2-0 |
| Portugal - Primeira Liga | 2021/03/08 20:15 | Belenenses v Benfica | W | 0-3 |
| Portugal - Cup | 2021/03/04 20:15 | Benfica v Estoril | W | 2-0 |
Away History
| Portugal - Primeira Liga | 2021/04/21 14:30 | Santa Clara v Moreirense | D | 0-0 |
| Portugal - Primeira Liga | 2021/04/17 14:30 | Guimaraes v Santa Clara | L | 1-0 |
| Portugal - Primeira Liga | 2021/04/11 14:30 | Santa Clara v Nacional | W | 5-1 |
| Portugal - Primeira Liga | 2021/04/03 19:30 | FC Porto v Santa Clara | L | 2-1 |
| Portugal - Primeira Liga | 2021/03/20 15:30 | Santa Clara v Tondela | D | 1-1 |
| Portugal - Primeira Liga | 2021/03/13 18:00 | Santa Clara v Portimonense | W | 2-0 |
| Portugal - Primeira Liga | 2021/03/05 20:45 | Sporting v Santa Clara | L | 2-1 |
| Portugal - Primeira Liga | 2021/02/27 18:00 | Santa Clara v Pacos Ferreira | W | 3-0 |